intel extreme tuning utility advanced tuning greyed out

Only have Throttle stop 9.2 tried beta 9.22 same thing. Have restored all settings to stock and totally uninstalled XTU. save immediately does not work, save when close does not work. Ran as administrator even though I have admin privileges. I have tried everything even set file properties for everyone to full control. I don't know why tried everything.have a registry hack that gives me several power boost options in processor boost settings nothing changes in the problem. I tried to use Throttlestop but it will NOT keep or save settings. no computer power is used to run external cooling. Machine has massive cooling, heat sinks added to the cpu and heat pipe O polar heat vacuum, Notebook fan control at 100 percent and a cooling pad which has 2 12 Volt fans at full rpm powered by external 12 v power, machine at idles at 29C maxes at 72. However the settings do not change back to defaults in XTU, This is an intermittent issue. For no reason it sometimes just drops to the OEM setting of 15 TDP. 050, Turbo Boost short power max at 30 W, Turbo Boost power max factory is 15 have it set at 30, Using Afterburner with Valley I see max temp of 72.

Intel extreme tuning utility advanced tuning greyed out